enough is enough

Do you ever feel that no matter how hard you try or how whole heartedly you pour yourself into something or someone, that it just never seems to be enough? How much more do you keep on trying before you tell yourself, “I gave it my best shot? “ How much more do you continue to tolerate physical and emotional neglect , essentially abuse? How much more will you continue to feel lonely although, they maybe in the same room but seem to be emotionally and mentally detached, essentially not present. I can't answer when enough is enough for someone but I can say that when it happens, I hope it serves as a wakeup call for all involved.